SARS-CoV-2 susceptibility – Communicable Diseases Research

Host Genetic Risk Factors Associated with COVID-19 Susceptibility and Severity in Vietnamese

Article

Published on 2022-10-182022-11-16
Journal: Genes
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

Distinct evolutionary trajectories of SARS-CoV-2-interacting proteins in bats and primates identify important host determinants of COVID-19

박쥐와 영장류에서 SARS-CoV-2 상호작용 단백질의 뚜렷한 진화 궤적은 COVID-19의 중요한 숙주 결정 요인을 식별합니다

Article

Published on 2022-08-302022-09-11
Journal: Proceedings of the National Academy of Sciences of
[Category] SARS, 치료기술, 치료제,

[키워드] ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptation adaptive analysis Arm arms race autophagy bat bats caused clinical trial comparative genetics coronavirus coronavirus coronavirus disease COVID-19 COVID-19 severity detection determinant Epidemics functional FYCO1 Genes Genetic genetic determinant Genome genomes Host humans identify in vivo Inflammation Inflammatory involved loci mammalian occurred pandemic Pathogenesis performed Phosphorylation positive Positive selection primates primates and bats Protein Regulation Replication residue residues RIPK1 SARS-CoV SARS-CoV-2 SARS-CoV-2 and COVID-19 SARS-COV-2 infection SARS-CoV-2 susceptibility severe acute respiratory syndrome Coronavirus severe COVID-19 severity signature susceptibility targets TMPRSS2 trajectory Vaccines virus virus–host coevolution.
[DOI] 10.1073/pnas.2206610119 PMC 바로가기 [Article Type] Article

Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults

비인두 미생물군집의 연령 관련 변화는 소아, 청소년 및 젊은 성인의 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 감염 및 증상과 관련이 있습니다

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 유전자 메커니즘,

[키워드] 16S ribosomal RNA Adults age association Bacterial change Characteristics childhood children Clinical data collected coronavirus 2 Corynebacterium Course COVID-19 Defense Dolosigranulum evaluated Factor feature generalized joint attribute modeling Host host defense identify Illness severity increasingly infected individuals influence joint less magnitude mechanism Microbiome microbiome composition microbiota nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs participant Pathogens pediatric pediatric microbiota. profile respiratory Respiratory pathogens respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility SARS-CoV-2-infected individual SARS-CoV-2-infected individuals Sequencing susceptibility susceptible Symptom upper respiratory
[DOI] 10.1093/cid/ciac184 PMC 바로가기 [Article Type] Article

Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections

세린 프로테아제 억제제는 SARS-CoV-2 감염에 대한 숙주 감수성을 제한합니다

Article

Published on 2022-06-282022-09-11
Journal: mBio
[Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제,

[키워드] A1AT acute respiratory syndrome Administered Affect affecting age Alpha alpha-1-antitrypsin antithrombin III antitrypsin Antiviral antiviral drug antiviral intervention approach asymptomatic infection asymptomatic infections ATIII can be used cellular cellular protease ciliated cleavage club Comorbidities Comorbidity complex coronavirus disease Coronavirus disease 2019 COVID-19 deficiency determinant determinants disease disease severity Donor door expression expression level Factor Genetic Genetic variation Genetic variations goblet cells highlight Host human donors identification identify identity immune response individual Infection inhibitor inhibitors less lung cell mechanism mechanism of action outcome PAI1 Patient patients plasminogen activator inhibitor 1 Potential potential treatments primary cell primary cells reduce reducing regulate restrict risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility Serine serine protease serine protease inhibitor serine protease inhibitors serpin serpin. SERPINA1 SERPINE1 SERPINE2 serpins Severe acute respiratory syndrome severe COVID-19 severe infections Sex Single-cell RNA sequencing Spike protein susceptibility susceptible Symptom target cells TMPRSS2 Treatment Usage Variation viral burden viral entry viral spike protein
[DOI] 10.1128/mbio.00892-22 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Infection Is Associated with Uncontrolled HIV Viral Load in Non-Hospitalized HIV-Infected Patients from Gugulethu, South Africa

SARS-CoV-2 감염은 남아프리카 구굴레투에서 입원하지 않은 HIV 감염 환자의 통제되지 않은 HIV 바이러스 부하와 관련이 있습니다

Observational Study

Published on 2022-06-032022-09-12
Journal: Viruses
[Category] COVID19(2023년), MERS, SARS, 임상, 진단,

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Erratum

Published on 2022-06-012022-10-05
Journal: Cell Reports
[Category] 유전자 메커니즘,

[키워드] affecting COVID-19 disease severity Gene Expression Genetic variant SARS-CoV-2 susceptibility variety of tissue
[DOI] 10.1016/j.celrep.2022.110968 [Article Type] Erratum

Systematic evaluating and modeling of SARS-CoV-2 UVC disinfection

SARS-CoV-2 UVC 소독의 체계적인 평가 및 모델링

Article

Published on 2022-04-072022-09-11
Journal: Scientific Reports
[Category] COVID19(2023년), SARS, 치료기술,

Coronavirus Resistance Database (CoV-RDB): SARS-CoV-2 susceptibility to monoclonal antibodies, convalescent plasma, and plasma from vaccinated persons

코로나 바이러스 저항 데이터베이스 (COV-RDB) : 백신 접종 된 사람의 단일 클론 항체, 회복기 혈장 및 혈장에 대한 SARS-COV-2 감수성

Research Article

Published on 2022-03-092022-09-10
Journal: PLoS ONE
[Category] MERS, SARS, 변종, 진단, 치료기술,

Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19

Genetics

Published on 2022-02-222022-10-31
Journal: Frontiers in Genetics
[Category] COVID-19,

[키워드] absence activating acute respiratory syndrome anti-SARS-CoV-2 Antiviral antiviral immunity Asymptomatic Biomarker cause Cell characterized class Cognate Combination constellation Control controls coronavirus Coronavirus-2 COVID-19 COVID-19 cohort COVID-19 host genetics COVID-19 patient COVID-19 susceptibility Defense determine detrimental Frequency General population Genetic healthy HLA HLA association HLA class I HLA gene HLA-Bw4 Host Hypothesis individual individuals Infection Inflammatory cytokine KIR KIR receptors KIR-HLA KIR-HLA association KIR2DL2 + KIR2DS1 KIR2DS5 KIR3DL1 KIR3DL2 Ligand ligands majority maturation natural NK cell NK cell function NK cells offer outcome pathologic Patient patients hospitalized receptor reduce regulated responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility severe COVID-19 severe COVID-19 patient significantly lower subsequent tested the patient triggered variable with mild disease
[DOI] 10.3389/fgene.2022.845474 PMC 바로가기 [Article Type] Genetics

Structural Bases of Zoonotic and Zooanthroponotic Transmission of SARS-CoV-2

SARS-COV-2의 동물성 및 동물원에서 Zooanthroponotic 전파의 구조적 염기

Review

Published on 2022-02-172022-09-10
Journal: Viruses
[Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, 조류인플루엔자,